The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2023

Filed:

Jun. 13, 2022
Applicant:

Caris Science, Inc., Irving, TX (US);

Inventors:

Clive Gavin Brown, Cambridge, GB;

Koen Kas, Schilde, BE;

Sven Agnes Jan Eyckerman, Nazareth, BE;

Assignee:

Caris Science, Inc., Irving, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6804 (2018.01); C12N 15/11 (2006.01); C12N 15/115 (2010.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6804 (2013.01); C12N 15/111 (2013.01); C12N 15/115 (2013.01); G01N 33/6818 (2013.01); C12N 2310/16 (2013.01); C12N 2320/11 (2013.01);
Abstract

The present invention is a method for measuring the amount of at least one molecule in a biological sample, the method comprising a) combining the sample, or a derivative thereof, with one or more aptamers and allowing one or more molecules in the sample to bind to the aptamer(s); b) separating bound from unbound molecules; and c) quantifying the molecule(s) bound to the or each aptamer, wherein quantification of the bound molecule(s) is carried out by sequencing at least part of the or each aptamer. Uses of and products derived from the method are also contemplated.


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