The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2023

Filed:

Sep. 25, 2018
Applicant:

California Institute of Technology, Pasadena, CA (US);

Inventors:

Rustem F. Ismagilov, Pasadena, CA (US);

Matthew S. Curtis, Pasadena, CA (US);

Mary Arrastia, Pasadena, CA (US);

David A. Selck, Pasadena, CA (US);

Mitchell Guttman, Pasadena, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); B01L 3/00 (2006.01); C12Q 1/6855 (2018.01); G01N 33/58 (2006.01); G01N 33/68 (2006.01); C12Q 1/6806 (2018.01); C40B 30/04 (2006.01); C40B 40/08 (2006.01); C40B 70/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1065 (2013.01); B01L 3/502715 (2013.01); B01L 3/502738 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6855 (2013.01); G01N 33/58 (2013.01); G01N 33/68 (2013.01); B01L 2200/027 (2013.01); B01L 2200/141 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/161 (2013.01); B01L 2400/065 (2013.01); C40B 30/04 (2013.01); C40B 40/08 (2013.01); C40B 70/00 (2013.01);
Abstract

Methods, systems and related compositions are provided to perform single-cell marking of a nucleic acid and/or protein in a sample based on in-cell or in-organelle barcoding of nucleic acid and/or protein complexes of the cell or organelle; the methods and systems herein described are configured to provide in-cell or in-organelle single-cell marked nucleic acid and/or protein complexes comprising a single-cell, cell-specific, or a single-cell organelle-specific marker.


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