The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2023

Filed:

Nov. 26, 2014
Applicants:

Kyoto Prefectural Public University Corporation, Kyoto, JP;

Actualeyes Inc., Kyoto, JP;

Corneagen, Inc., Seattle, WA (US);

Inventors:

Noriko Koizumi, Kyotanabe, JP;

Naoki Okumura, Kyotanabe, JP;

Shigeru Kinoshita, Kyoto, JP;

Friedrich E. Kruse, Erlangen, DE;

Ursula Schloetzer-Schrehardt, Erlangen, DE;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/079 (2010.01); A61K 35/30 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0621 (2013.01); A61K 35/30 (2013.01); C12N 2533/52 (2013.01);
Abstract

The present invention provides a method of culturing corneal endothelial cells. More specifically, the present invention provides a composition for culturing or growing corneal endothelial cells, comprising at least one agent consisting of laminins and fragments thereof which express in corneal endothelial cells. Specifically, the present invention can comprise laminin 511 (alpha5 beta1 gamma1) and laminin 512 (alpha5 beta2 gamma 1). The present invention further provides a culture container for corneal endothelial cells, which is coated with the composition of the present invention. Furthermore, the present invention provides a method for culturing corneal endothelial cells comprising the step of using the composition or the container of the present invention to culture the corneal endothelial cells.


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