The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2023
Filed:
Feb. 27, 2018
Applicants:
Caerus Therapeutics, Inc., Manassas, VA (US);
University of Georgia Research Foundation, Inc., Athens, GA (US);
Inventors:
J. Michael Pierce, Athens, GA (US);
Cohava Gelber, Nokesville, VA (US);
Assignees:
Caerus Therapeutics, Inc., Manassas, VA (US);
University of Georgia Research Foundation, Inc., Athens, GA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 35/17 (2015.01); G01N 33/574 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 35/17 (2013.01); C07K 16/303 (2013.01); C07K 16/3046 (2013.01); G01N 33/57419 (2013.01); G01N 33/57438 (2013.01); G01N 33/57473 (2013.01); A61K 38/00 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); G01N 2333/70596 (2013.01);
Abstract
Provided herein are antibodies and related polypeptides that bind specifically to CEACAM6. The antibodies and/or polypeptides can be configured as bispecific T cell engagers. The antibodies and/or polypeptides can also be configured as chimeric antigen receptors. Also provided are methods of detection and treatment of cancer, for example, pancreatic cancer, using the antibodies and related polypeptides herein.