The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2023

Filed:

Jun. 05, 2020
Applicant:

Ac Immune SA, Lausanne, CH;

Inventors:

Jérôme Molette, Prevessin Moens, FR;

Emanuele Gabellieri, Lausanne, CH;

Vincent Darmency, Bougy-Villars, CH;

Assignee:

AC IMMUNE SA, Lausanne, CH;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); C07D 417/14 (2006.01); C07D 513/04 (2006.01); A61K 51/04 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61K 51/0431 (2013.01); C07B 59/002 (2013.01); C07D 417/14 (2013.01); C07D 513/04 (2013.01); C07B 2200/05 (2013.01);
Abstract

The present invention relates to novel compounds that can be employed in the diagnosis, monitoring of disease progression or monitoring of drug activity, of a group of disorders and abnormalities associated with alpha-synuclein (α-synuclein, A-synuclein, aSynuclein, A-syn, α-syn, aSyn) aggregates including, but not limited to, Lewy bodies and/or Lewy neurites, such as Parkinson's disease. The instant compounds are particularly useful in determining a predisposition to such a disorder, monitoring residual disorder, or predicting the responsiveness of a patient who is suffering from such a disorder to the treatment with a certain medicament. The present compounds can also be used to treat, alleviate or prevent a disorder or abnormality associated with alpha-synuclein aggregates.


Find Patent Forward Citations

Loading…