The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2023

Filed:

Nov. 17, 2021
Applicants:

Southern Research Institute, Birmingham, AL (US);

Uab Research Foundation, Birmingham, AL (US);

The United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

Mark J. Suto, Homewood, AL (US);

Bini Mathew, Hoover, AL (US);

Anupam Agarwal, Mountain Brook, AL (US);

Amie M. Traylor, Talladega, AL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/36 (2006.01); C07D 215/40 (2006.01); C07D 215/48 (2006.01); C07D 213/70 (2006.01); C07D 217/22 (2006.01); C07C 321/28 (2006.01);
U.S. Cl.
CPC ...
C07D 215/36 (2013.01); C07C 321/28 (2013.01); C07D 213/70 (2013.01); C07D 215/40 (2013.01); C07D 215/48 (2013.01); C07D 217/22 (2013.01);
Abstract

The present disclosure is concerned with thioquinolinone compounds for the treatment of disorders associated with heme oxygenase-1 (HO-1) signaling dysfunction such as, for example, kidney diseases (e.g., chronic kidney disease, acute kidney injury). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.


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