The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2023

Filed:

Jan. 14, 2021
Applicant:

Amicus Therapeutics, Inc., Cranbury, NJ (US);

Inventors:

Kamlesh Sheth, North Brunswick, NJ (US);

Sergey Tesier, Monroe, NJ (US);

James Cartwright, Middlesex, GB;

Clive King, Middlesex, GB;

Wendy Cross, Middlesex, GB;

Assignee:

Amicus Therapeutics, Inc., Philadelphia, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/46 (2006.01); A61J 1/03 (2023.01); G01N 15/08 (2006.01); G01N 33/15 (2006.01); G16H 20/10 (2018.01);
U.S. Cl.
CPC ...
C07D 211/46 (2013.01); A61J 1/035 (2013.01); G01N 15/0826 (2013.01); G01N 33/15 (2013.01); C07B 2200/13 (2013.01); G16H 20/10 (2018.01);
Abstract

Provided are methods of producing a batch of 1,2,3,6-tetrapivaloyl-D-galactofuranoside; 5-azido-5-deoxy-1,2,3,6-tetrapivaloyl-D-galactofuranoside; intermediate grade migalastat hydrochloride; and/or migalastat hydrochloride. Also provided are methods of determining the purity of a batch of 1,2,3,6-tetrapivaloyl-D-galactofuranoside; 5-azido-5-deoxy-1,2,3,6-tetrapivaloyl-D-galactofuranoside; intermediate grade migalastat hydrochloride; and/or migalastat hydrochloride. Also provided are methods of distributing a batch of 1,2,3,6-tetrapivaloyl-D-galactofuranoside; 5-azido-5-deoxy-1,2,3,6-tetrapivaloyl-D-galactofuranoside; intermediate grade migalastat hydrochloride; and/or migalastat hydrochloride. Also provided are methods of assessing suitability of migalastat hydrochloride for medical use.


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