The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 2023

Filed:

Apr. 04, 2018
Applicant:

Miroculus Inc., San Francisco, CA (US);

Inventors:

Mais J. Jebrail, Toronto, CA;

Alexandra Judy Cho, Toronto, CA;

Foteini Christodoulou, San Francisco, CA (US);

Assignee:

mirOculus Inc., San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01L 7/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502792 (2013.01); B01L 3/502761 (2013.01); B01L 7/525 (2013.01); B01L 2200/0647 (2013.01); B01L 2200/0673 (2013.01); B01L 2200/142 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0809 (2013.01); B01L 2300/18 (2013.01); B01L 2400/0427 (2013.01);
Abstract

Air-matrix digital microfluidics (DMF) apparatuses and methods of using them to prevent or limit evaporation and surface fouling of the DMF apparatus. In particular, described herein are air-matrix DMF apparatuses and methods of using them including thermally controllable regions with a wax material that may be used to selectively encapsulate a reaction droplet in the air gap of the apparatus; additional aqueous droplets may be combined with the encapsulated droplet even after separating from the wax, despite residual wax coating, by merging with an aqueous droplet having a coating of a secondary material (e.g., an oil or other hydrophobic material) that may remove the wax from the droplet and/or allow combining of the droplets.


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