The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2023
Filed:
Oct. 12, 2016
Nantomics, Llc, Culver City, CA (US);
Patrick Soon-Shiong, Los Angeles, CA (US);
Stephen Charles Benz, Santa Cruz, CA (US);
Andrew Nguyen, San Jose, CA (US);
Shahrooz Rabizadeh, Los Angeles, CA (US);
Kayvan Niazi, Los Angeles, CA (US);
Oleksandr Buzko, Culver City, CA (US);
Jay Gardner Nelson, Culver City, CA (US);
NantOmics, LLC, Culver City, CA (US);
Abstract
Methods and compositions for preparation and use of recombinant viruses or other recombinant expression systems are presented in which neoepitopes are first identified in a patient- and cancer-specific manner and then further filtered by HLA-match to the patient. Selected neoepitopes are then expression using sequence elements that direct the expressed neoepitope to the HLA-type (MHC-I and/or MHC-II subtype) that has desirable affinity to the filtered neoepitope.