The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 11, 2023
Filed:
Dec. 06, 2017
Vap polypeptide and use thereof in preparation of drug for targeted diagnosis and treatment of tumor
Applicant:
Fudan University, Shanghai, CN;
Inventors:
Assignee:
FUDAN UNIVERSITY, Shanghai, CN;
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2019.01); A61K 47/64 (2017.01); C07K 7/06 (2006.01); A61K 9/127 (2006.01); A61K 31/337 (2006.01); A61K 31/42 (2006.01); A61K 31/64 (2006.01); A61K 31/704 (2006.01); A61K 47/34 (2017.01); A61K 49/14 (2006.01); A61K 39/00 (2006.01); A61K 9/107 (2006.01);
U.S. Cl.
CPC ...
A61K 38/08 (2013.01); A61K 9/127 (2013.01); A61K 31/337 (2013.01); A61K 31/42 (2013.01); A61K 31/64 (2013.01); A61K 31/704 (2013.01); A61K 39/0011 (2013.01); A61K 47/34 (2013.01); A61K 47/64 (2017.08); A61K 49/14 (2013.01); C07K 7/06 (2013.01); A61K 9/107 (2013.01);
Abstract
Provided in the present invention are highly stable D-configuration polypeptides DVAP and SVAP having a high binding activity to the GRP78 protein, and also provided are an L-configuration polypeptide LVAP and a DVAP-or SVAP-modified model drug and a macromolecule carrier material, and the use thereof in the construction of a tumour image and a drug-delivery system for targeted treatment.