The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 04, 2023

Filed:

Jan. 14, 2019
Applicant:

Universität Heidelberg, Heidelberg, DE;

Inventors:

Markus Hecker, Heidelberg, DE;

Andreas Wagner, Heidelberg, DE;

Andreas Jungmann, Neckargemünd, DE;

Oliver Müller, Heikendorf, DE;

Anca Remes, Kiel, DE;

Hugo Katus, Heidelberg, DE;

Assignee:

Universität Heidelberg, Heidelberg, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61K 31/713 (2006.01); C07H 21/00 (2006.01); C12N 15/113 (2010.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4702 (2013.01); A61K 31/713 (2013.01); C07H 21/00 (2013.01); C12N 15/113 (2013.01); A61K 38/00 (2013.01); C12N 2310/13 (2013.01);
Abstract

The present invention relates to a polynucleotide comprising a Nuclear factor of activated T-cells (NFAT) binding site sequence and a reverse complement of said NFAT binding site sequence separated by a spacer sequence, to said polynucleotide for use in treating and/or preventing disease, and to viral particles, compositions, and uses related thereto. The present invention further relates to a polynucleotide comprising a Nuclear factor of activated T-cells (NFAT) binding site sequence and a reverse complement of said NFAT binding site sequence for use in treating and/or preventing an NFAT-mediated disease.


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