The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2023
Filed:
Jan. 16, 2021
Applicants:
Case Western Reserve University, Cleveland, OH (US);
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Inventors:
Jeffery M. Coller, Cleveland, OH (US);
Thomas Sweet, Cleveland, OH (US);
Harvey Lodish, Cambridge, MA (US);
Assignees:
CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61P 25/08 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0066 (2013.01); A61P 25/08 (2018.01);
Abstract
Modified tRNAs can be used to express in a mammalian cell a functional gene product encoded by a gene containing a premature stop codon and/or to treat a disease mediated by a premature stop codon.