The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2023
Filed:
Dec. 20, 2012
Applicant:
Bayer Pharma Ag, Berlin, DE;
Inventor:
Kristina King, Berlin, DE;
Assignee:
BAYER PHARMA AG, Berlin, DE;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/565 (2006.01); A61K 31/00 (2006.01); A61K 31/56 (2006.01); A61K 31/4985 (2006.01); A61K 31/567 (2006.01); B82Y 5/00 (2011.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/00 (2013.01); A61K 31/4985 (2013.01); A61K 31/56 (2013.01); A61K 31/565 (2013.01); A61K 31/567 (2013.01); A61K 47/6951 (2017.08); B82Y 5/00 (2013.01);
Abstract
The present invention relates to solid pharmaceutical compositions, in particular to oral contraceptives, comprising a progestogen, such as drospirenone; an estrogen, such as ethinylestradiol; a tetrahydrofolic acid or a pharmaceutically acceptable salt thereof, such as calcium 5-methyl-(6S)-tetrahydrofolate; and at least one pharmaceutical acceptable excipient or carrier. The compositions of the invention provide good stability of the tetrahydrofolic acid upon storage while still ensuring a fast and reliable release of the estrogen and the progestogen present in the composition.