The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 04, 2023
Filed:
Aug. 26, 2019
Applicant:
Acetylon Pharmaceuticals, Inc., Boston, MA (US);
Inventors:
John H. van Duzer, Georgetown, MA (US);
Ralph Mazitschek, Belmont, MA (US);
Walter Ogier, Winchester, MA (US);
James E. Bradner, Cambridge, MA (US);
Guoxiang Huang, Kernersville, NC (US);
Dejian Xie, Shanghai, CN;
Nan Yu, Shanghai, CN;
Assignee:
Acetylon Pharmaceuticals, Inc., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 235/30 (2006.01); C07D 239/42 (2006.01); C07D 241/20 (2006.01); C07C 259/06 (2006.01); C07D 213/74 (2006.01); C07D 277/82 (2006.01); C07D 209/48 (2006.01); C07D 401/12 (2006.01); C07D 417/06 (2006.01); C07D 213/81 (2006.01); C07D 401/06 (2006.01); C07D 403/04 (2006.01); C07D 213/30 (2006.01); C07D 277/24 (2006.01); C07D 209/46 (2006.01); C07D 413/04 (2006.01); C07D 401/04 (2006.01); C07D 263/58 (2006.01); C07C 237/36 (2006.01); A61K 31/505 (2006.01); A61K 31/164 (2006.01); A61K 31/337 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/505 (2013.01); A61K 31/164 (2013.01); A61K 31/337 (2013.01); A61K 45/06 (2013.01); C07C 237/36 (2013.01); C07C 259/06 (2013.01); C07D 209/46 (2013.01); C07D 209/48 (2013.01); C07D 213/30 (2013.01); C07D 213/74 (2013.01); C07D 213/81 (2013.01); C07D 235/30 (2013.01); C07D 239/42 (2013.01); C07D 241/20 (2013.01); C07D 263/58 (2013.01); C07D 277/24 (2013.01); C07D 277/82 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01); C07D 413/04 (2013.01); C07D 417/06 (2013.01);
Abstract
The present invention relates to novel 'reverse amide' compounds comprising a zinc chelator group, and the use of such compounds in the inhibition of HDAC6 and in the treatment of various diseases, disorders or conditions related to HDAC6.