The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 04, 2023

Filed:

Sep. 27, 2017
Applicants:

Sogang University Research Foundation, Seoul, KR;

Seoul National University R&db Foundation, Seoul, KR;

Imgt Co, Ltd., Seongnam-si, KR;

Inventors:

Hyun Cheol Kim, Seoul, KR;

Jin Wook Chung, Seoul, KR;

Eun Ah Jung, Seoul, KR;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 9/16 (2006.01); A61K 31/337 (2006.01); A61K 31/396 (2006.01); A61K 31/7068 (2006.01); A61K 47/42 (2017.01); A61K 49/04 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5169 (2013.01); A61K 9/1658 (2013.01); A61K 31/337 (2013.01); A61K 31/396 (2013.01); A61K 31/7068 (2013.01); A61K 47/42 (2013.01); A61K 49/04 (2013.01);
Abstract

The present invention aims to dramatically increase the effect of hepatic arterial chemoembolization by developing human serum albumin-based nanoparticles, which are bioproteins that effectively carry Adriamycin in place of Adriamycin, an anticancer agent used in hepatic arterial chemoembolization. The human serum albumin nanoparticles carrying the Adriamycin not only intensively infiltrate the drug effectively into the cells but also have a synergistic effect that can induce a long-term therapeutic effect by utilizing the effect of continuous drug release from the particles.


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