The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2023
Filed:
Jun. 29, 2018
Kolon Life Science, Inc., Seoul, KR;
Kolon Tissuegene, Inc., Rockville, MD (US);
Su Jeong Kim, Seoul, KR;
Sang Eun Noh, Incheon, KR;
Jun Ho Lee, Seoul, KR;
Hyeon Youl Lee, Gyeonggi-do, KR;
Kyoung Baek Choi, Incheon, KR;
Heon Sik Choi, Seoul, KR;
KOLON LIFE SCIENCE, INC., Seoul, KR;
KOLON TISSUEGENE, INC., Rockville, MD (US);
Abstract
The present invention provides a method for evaluating effectiveness of a cell therapeutic agent. When using TGF-β and/or TSP-1 expression level(s) in: (a) a first population of transformed mammalian cells with TGF-β; and (b) a second population of untransformed mammalian cells with the same gene, respectively, as a criterion for determining effectiveness of a cell therapeutic agent, and whether or not expression thereof, it is possible to definitely determine the therapeutic efficacy of each cell therapeutic agent prior to initiation of the treatment. In addition, since use of a cell therapeutic agent without therapeutic effects is avoided, undesired procedures and side effects may not be entailed.