The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2023

Filed:

Jan. 09, 2018
Applicant:

Onkosxcel Therapeutics, Llc, New Haven, CT (US);

Inventors:

Krishnan Nandabalan, New Haven, CT (US);

Luca Rastelli, New Haven, CT (US);

Assignee:

OnkosXcel Therapeutics, LLC, New Haven, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); G16B 25/10 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); G16B 25/10 (2019.02); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01);
Abstract

The present invention generally relates to a method of diagnosing, prognosing and treating prostate cancer patients. Particularly, the present invention relates to a method of selecting patients with castration resistant prostate cancer (CrPC) for combination therapy comprising a selective dipeptidyl peptidase inhibitor and a PD-1 axis antagonist. The present invention provides a computational approach to identifying potential patients for CrPC. The present invention also relates to a method of treating castration resistant prostate cancer (CrPC) patients with said combination therapy.


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