The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2023
Filed:
Apr. 13, 2018
Applicant:
Regenxbio Inc., Rockville, MD (US);
Inventors:
Stephen Yoo, Newton, MA (US);
Rickey Robert Reinhardt, Silver Spring, MD (US);
Curran Matthew Simpson, Frederick, MD (US);
Zhuchun Wu, Potomac, MD (US);
Assignee:
REGENXBIO Inc., Rockville, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/16 (2006.01); A61P 3/00 (2006.01); A61K 9/00 (2006.01); A61K 35/76 (2015.01); C12N 15/86 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/16 (2013.01); A61K 9/0043 (2013.01); A61K 9/0085 (2013.01); A61K 35/76 (2013.01); A61P 3/00 (2018.01); C12N 15/86 (2013.01); C12Y 301/06013 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C12N 2750/14121 (2013.01); C12N 2750/14132 (2013.01); C12N 2750/14143 (2013.01);
Abstract
Compositions and methods are described for the delivery of recombinant human iduronate-2-sulfatase (IDS) produced by human neuronal or glial cells to the cerebrospinal fluid of the central nervous system (CNS) of a human subject diagnosed with mucopolysaccharidosis II (MPS II).