The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2023
Filed:
Mar. 17, 2020
Applicant:
The Florida State University Research Foundation, Inc., Tallahassee, FL (US);
Assignee:
The Florida State University Research Foundation, Inc., Tallahassee, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/079 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0618 (2013.01); C12N 2501/165 (2013.01); C12N 2501/20 (2013.01); C12N 2501/999 (2013.01); C12N 2502/08 (2013.01); C12N 2502/088 (2013.01); C12N 2502/1352 (2013.01); C12N 2502/28 (2013.01); C12N 2513/00 (2013.01); C12N 2533/80 (2013.01);
Abstract
Improved hybrid neurovascular spheroids and methods for making the same are provided. In some embodiments of a method for making a hybrid neurovascular spheroid, the method includes i) propagating cortical cells to form a cortical spheroid; ii) propagating endothelial cells to form an endothelial spheroid; iii) propagating mesenchymal stem cells to form a mesenchymal cell culture; and iv) combining the cortical spheroid, endothelial spheroid, and mesenchymal spheroid under conditions to form the hybrid neurovascular spheroid.