The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2023

Filed:

Aug. 09, 2019
Applicant:

Kyowa Hakko Bio Co., Ltd., Tokyo, JP;

Inventors:

Tohru Dairi, Sapporo, JP;

Yasuharu Satoh, Sapporo, JP;

Shohei Hayashi, Sapporo, JP;

Mai Naka, Sapporo, JP;

Tetsuro Ujihara, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/10 (2006.01); C12N 15/70 (2006.01); C12P 7/64 (2022.01); C12R 1/90 (2006.01);
U.S. Cl.
CPC ...
C12N 1/105 (2021.05); C12N 15/70 (2013.01); C12P 7/64 (2013.01); C12R 2001/90 (2021.05);
Abstract

An object of the present invention is to provide a microorganism that efficiently produces EPA and a method for producing EPA using the microorganism. The present invention relates to a microorganism having an ability to produce docosahexaenoic acid (DHA), wherein the microorganism contains a protein composed of an amino acid sequence in which at least one of the amino acid residues at positions 6, 65, 230, 231, and 275 in the amino acid sequence represented by SEQ ID NO: 2 has been substituted with another amino acid residue (mutated OrfB), and is capable of producing eicosapentaenoic acid (EPA), and the like.


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