The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2023
Filed:
Aug. 15, 2018
Inflazome Limited, Dublin, IE;
Matthew Cooper, Cambridge, GB;
David Miller, Cambridge, GB;
Angus Macleod, Cambridge, GB;
Stephen Thom, Nottingham, GB;
Stephen St-Gallay, Nottingham, GB;
Jonathan Shannon, Nottingham, GB;
Thomas Alanine, Nottingham, GB;
Stuart Onions, Nottingham, GB;
Ian Strutt, Nottingham, GB;
Jokin Carrillo Arregui, Nottingham, GB;
Inflazome Limited, Dublin, IE;
Abstract
The present invention relates to sulfonylureas and sulfonylthioureas comprising a 5-membered nitrogen-containing heteroaryl ring attached to the sulfonyl group, wherein the heteroaryl ring is substituted with a nitrogen-containing group R' wherein Rcontains from 1 to 7 atoms other than hydrogen or halogen. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the inhibition of NLRP.