The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2023

Filed:

Apr. 23, 2021
Applicant:

Eli Lilly and Company, Indianapolis, IN (US);

Inventors:

Erin D. Anderson, Boulder, CO (US);

Steven W. Andrews, Longmont, CO (US);

Kevin R. Condroski, Lafayette, CO (US);

Thomas C. Irvin, Erie, CO (US);

Gabrielle R. Kolakowski, Longmont, CO (US);

Manoj Kumar, Longmont, CO (US);

Elizabeth A. McFaddin, Nederland, CO (US);

Megan McKenney, Boulder, CO (US);

Michael J. Munchhof, Corvallis, MT (US);

Michael B. Welch, Westminster, CO (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); C07D 231/38 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); C07D 231/38 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07B 2200/05 (2013.01);
Abstract

Provided herein are RET kinase inhibitors according to the formula: pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods for their use in the treatment of diseases that can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders. A, R, n, X, X, X, X, and Rhave the meanings given in the specification.


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