The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2023

Filed:

Oct. 08, 2021
Applicant:

Kalvista Pharmaceuticals Limited, Porton Down, GB;

Inventors:

Rebecca Louise Davie, Porton Down, GB;

Hannah Joy Edwards, Porton Down, GB;

David Michael Evans, Porton Down, GB;

Simon Teanby Hodgson, Ampthill, GB;

Alessandro Mazzacani, Porton Down, GB;

Michael John Stocks, Leicestershire, GB;

Thomas Matthew Baker, Nottingham, GB;

Matthew Robert Conroy, Nottingham, GB;

Alun John Smith, Nottingham, GB;

David Edward Clark, Harlow, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 487/04 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/08 (2006.01); C07D 491/107 (2006.01); C07D 491/147 (2006.01); C07D 491/20 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 487/08 (2013.01); C07D 491/107 (2013.01); C07D 491/147 (2013.01); C07D 491/20 (2013.01);
Abstract

The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, W, X, Y and Z are as defined herein.


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