The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2023

Filed:

Oct. 18, 2017
Applicant:

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Michael S. Bono, Somerville, MA (US);

Sydney B. Beasley, Cambridge, MA (US);

Emily Barret Hanhauser, Brookline, MA (US);

Chintan Vaishnav, Belmont, MA (US);

Anastasios John Hart, Waban, MA (US);

Rohit Nandkumar Karnik, Cambridge, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/10 (2006.01); B01D 35/06 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
B01D 35/06 (2013.01); B01L 3/502715 (2013.01); G01N 1/10 (2013.01); B01L 2300/0681 (2013.01); G01N 2001/1062 (2013.01);
Abstract

Systems, devices, and methods for detecting contamination (e.g., bacteria) in fluid are provided. The systems, devices, and methods allow for filtering a fluid sample using a filter to capture and concentrate cells (e.g., bacteria) to detect electrochemical properties thereof. The cells can be exposed to a reagent that diffuses into the cells to produce a product of interest that can be used in analysis of the fluid sample. The product of interest can diffuse out of the filter into a fluid storage component for detection and analysis by an analysis component. After the sampling is completed, the filter can be detached and discarded. Other aspects of the present disclosure, including enhancements and various systems and methods for concentrating cells and analyzing the same, are also provided.


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