The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2023
Filed:
May. 06, 2022
Applicant:
Defence Therapeutics Inc., Vancouver, CA;
Inventor:
Simon Beaudoin, Sherbrooke, CA;
Assignee:
DEFENCE THERAPEUTICS INC., Vancouver, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/50 (2017.01); A61P 31/14 (2006.01); A61K 39/385 (2006.01); A61K 47/54 (2017.01); A61K 47/64 (2017.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/385 (2013.01); A61K 47/542 (2017.08); A61K 47/554 (2017.08); A61K 47/64 (2017.08); A61P 31/14 (2018.01); A61K 2039/6006 (2013.01); A61K 2039/6031 (2013.01);
Abstract
Immunogen enhancers for admixture with an antigen of interest are described herein. The enhancers generally comprise a steroid acid and/or a steroid acid-peptide conjugate in an amount sufficient to improve or modify the adaptive immune response to antigens admixed therewith. In embodiments, the steroid acid may be a bile acid and the peptide may comprise one or more functional domains, such as a nuclear localization signal, which may facilitate antigen-presentation and/or antigen cross-presentation, thereby triggering improved cellular immunity, or improved cellular and humoral immunity, against the antigen.