The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 21, 2023

Filed:

Sep. 30, 2021
Applicant:

Gentian As, Moss, NO;

Inventors:

Ingvild Gudim, Moss, NO;

Torsten Knüttel, Ski, NO;

Berit Løseth, Oslo, NO;

Christian Melbø-Jørgensen, Moss, NO;

Tom Nilsen, Moss, NO;

Erling Sundrehagen, Moss, NO;

Ly Thi Tran, Moss, NO;

Jie Yang, Drammen, NO;

Assignee:

Gentian AS, Moss, NO;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); C07K 16/26 (2006.01); G01N 21/17 (2006.01); G01N 33/74 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54313 (2013.01); C07K 16/26 (2013.01); G01N 21/17 (2013.01); G01N 33/74 (2013.01); C07K 2317/23 (2013.01); C07K 2317/34 (2013.01); C07K 2317/92 (2013.01); G01N 2333/58 (2013.01); G01N 2800/325 (2013.01);
Abstract

NT-proBNP can be determined in a biological sample using at least one antibody which recognizes an epitope of NT-proBNP in both a glycosylated and non-glycosylated form of NT-proBNP. Said antibody is preferably an isolated polyclonal antibody or a mixture of monoclonal antibodies coated onto a particle, preferably coated onto said particle in a coating ratio of 6-60%, forming a layer or multiple layers of antibodies on said particle. The assay, realized in the form of a nephelometric or turbidimetric assay, can be applied to a wide range of automated clinical analyzers.


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