The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2023
Filed:
Apr. 20, 2017
Ecole Normale Superieure DE Lyon, Lyons, FR;
Centre National DE LA Recherche Scientifique (Cnrs), Paris, FR;
Université Claude Bernard Lyon 1, Villeurbanne, FR;
Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;
Caroline Costa Fejoz, Lyons, FR;
Els Verhoeyen, Nice, FR;
François-Loïc Cosset, Lyons, FR;
Ruben Bender, Frankfurt, DE;
Christian Buchholz, Frankfurt, DE;
Qi Zhou, Hitchin, GB;
Ecole Normale Superieure de Lyon, Lyons, FR;
Centre National de la Recherche Scientifique (CNRS), Paris, FR;
Université Claude Bernard Lyon 1, Villeurbanne, FR;
Institut National de la Sante et de la Recherche Medicale (INSERM), Paris, FR;
Abstract
The present invention relates to pseudotyped retrovirus-like particles or retroviral vectors comprising both engineered envelope glycoproteins derived from a virus of the Paramyxoviridae family fused to a cell targeting domain and fused to a functional domain. The present invention also relates to the use of said pseudotyped retrovirus-like particles or retroviral vectors to selectively modulate the activity of specific subsets of cells, in particular of specific immune cells. These pseudotyped retrovirus-like particles or retroviral vectors are particularly useful for gene therapy, immune therapy and/or vaccination.