The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2023
Filed:
Apr. 20, 2017
Applicant:
Basf Plant Science Company Gmbh, Ludwigshafen am Rhein, DE;
Inventors:
Leendert W. Neuteboom, Research Triangle Park, NC (US);
John A. McElver, Research Triangle Park, NC (US);
Rosa De Pinho Barroco, Ghent, BE;
Chris De Wilde, Ghent, BE;
Max Fabian Felle, Ludwigshafen, DE;
Assignee:
BASF PLANT SCIENCE COMPANY GMBH, Ludwigshafen, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/10 (2006.01); C12N 15/70 (2006.01); C12N 15/75 (2006.01); C12N 15/82 (2006.01); C12N 15/85 (2006.01); C12N 15/90 (2006.01); C12N 15/81 (2006.01);
U.S. Cl.
CPC ...
C12N 15/11 (2013.01); C12N 15/102 (2013.01); C12N 15/111 (2013.01); C12N 15/70 (2013.01); C12N 15/75 (2013.01); C12N 15/81 (2013.01); C12N 15/8274 (2013.01); C12N 15/8509 (2013.01); C12N 15/902 (2013.01); C12N 15/905 (2013.01); C12N 15/907 (2013.01); C12N 2310/20 (2017.05);
Abstract
Methods for modification of target nucleic acids. The method involves a construct in which guide RNA is covalently linked to donor RNA (fusion NA) to be introduced into the target nucleic acid by homologous recombination and is based on the introduction of a nuclease, e.g. CRISPR or TALEN, into the cell containing the target nucleic acid. The fusion NA may be introduced as a DNA vector.