The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2023
Filed:
Apr. 04, 2018
Applicant:
Xdcexplorer (Shanghai) Co., Ltd., Shanghai, CN;
Inventors:
Ying Zhang, Shanghai, CN;
Shiyong Gong, Shanghai, CN;
Xiaolan Sun, Shanghai, CN;
Tengjiao Xu, Shanghai, CN;
Fei Peng, Shanghai, CN;
Yuzhu Chen, Shanghai, CN;
Lile Liu, Shanghai, CN;
Assignee:
XDCEXPLORER (SHANGHAI) CO., LTD., Shanghai, CN;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); C12N 15/63 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61K 47/6851 (2017.08); A61P 35/00 (2018.01); C12N 15/63 (2013.01); G01N 33/56966 (2013.01);
Abstract
The present invention provides a humanized anti-TPBG antibody, a preparation method therefor, a conjugate thereof, and applications. The humanized anti-TPBG antibody comprises: (a), a framework region comprising a residue of a human antibody framework region; and (b) one or more CDRs of a light-chain variable region as shown in the SEQ ID NO:4 or 8 or one or more CDRs of a heavy-chain variable region as shown in the SEQ ID NO:2 or 6.