The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2023
Filed:
Oct. 26, 2018
Green Cross Holdings Corporation, Gyeonggi-do, KR;
Jee Won Ahn, Seoul, KR;
Kwan Young Ko, Gyeonggi-do, KR;
Jeong Hye Yoon, Gyeonggi-do, KR;
Seung-Ho Baek, Gyeonggi-do, KR;
Min Jung Kim, Seoul, KR;
Geun Hye Yeo, Gyeonggi-do, KR;
Jung-Ae Lim, Gyeonggi-do, KR;
Soo-kwang Kim, Gyeonggi-do, KR;
GREEN CROSS HOLDINGS CORPORATION, Gyeonggi-Do, KR;
Abstract
Disclosed is a method for preparing a composition comprising factor VIII (FVIII) and von Willebrand factor (vWF), wherein the content of the von Willebrand factor (vWF) can be controlled by mixing the factor VIII (FVIII) with the von Willebrand factor (vWF) at an appropriate ratio after separately purifying the factor VIII (FVIII) and the von Willebrand factor (vWF) from plasma in a single process. The method can prepare and purify a composition comprising factor VIII (FVIII) and a varying content of von Willebrand factor (vWF) without increasing the amount of impurities other than the von Willebrand factor (vWF) compared to a method of purifying factor VIII (FVIII) separately, without significantly increasing the processing time (within 3 hours) compared to a method of purifying factor VIII (FVIII), and without changing the yield of factor VIII (FVIII).