The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 21, 2023

Filed:

Dec. 19, 2018
Applicants:

Puretech Lyt, Inc., Boston, MA (US);

Monash University, Clayton, AU;

Inventors:

Daniel Kenneth Bonner, Sharon, MA (US);

Sifei Han, Clayton, AU;

Luojuan Hu, Clayton, AU;

Ketki Karanam, Newton, MA (US);

Christopher John Porter, Clayton, AU;

Tim Quach, Clayton, AU;

Rishab R. Shyam, Arlington, MA (US);

Jamie Simpson, Chestnut Hill, MA (US);

Natalie Trevaskis, Clayton, AU;

Assignees:

PureTech LYT, Inc., Boston, MA (US);

Monash University, Clayton, AU;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/18 (2006.01); A61P 37/06 (2006.01);
U.S. Cl.
CPC ...
C07D 498/18 (2013.01); A61P 37/06 (2018.01);
Abstract

The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.


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