The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2023
Filed:
Aug. 11, 2017
Jiangsu Hansoh Pharmaceutical Group Co., Ltd., Jiangsu, CN;
Shanghai Hansoh Biomedical Co., Ltd., Shanghai, CN;
Peng Gao, Jiangsu, CN;
Guangjun Sun, Jiangsu, CN;
Songliang Tan, Jiangsu, CN;
Lei Liu, Jiangsu, CN;
Rudi Bao, Jiangsu, CN;
Jiangsu Hansoh Pharmaceutical Group Co., Ltd., Jiangsu, CN;
Shanghai Hansoh Biomedical Co., Ltd., Shanghai, CN;
Abstract
Provided are an FGFR4 inhibitor with the structure of formula (I) and a preparation method and use thereof. The series of compounds of formula (I) have a very strong inhibitory effect on the FGFR4 kinase activity, and have a very high selectivity; and the same can be widely used to prepare drugs for treating cancers, in particular, liver cancer, stomach cancer, prostate cancer, skin cancer, ovarian cancer, lung cancer, breast cancer or colon cancer, and it is expected that the same can be developed into a new generation of FGFR4 inhibitor drugs.