The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 21, 2023

Filed:

Jun. 04, 2021
Applicant:

University of Sharjah, Sharjah, AE;

Inventors:

Sameh S. M. Soliman, Sharjah, AE;

Bahgat Fayed, Sharjah, AE;

Rania Hamdy, Sharjah, AE;

Ahmed M. Almehdi, Sharjah, AE;

Assignee:

UNIVERSITY OF SHARJAH, Sharjah, AE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01); A61P 31/14 (2006.01); C07D 413/14 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); A61P 31/14 (2018.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01);
Abstract

The present invention discloses novel SARS-CoV-2 inhibitors for therapeutic formulations and methods for treating SARS-CoV-2 infections. The compounds exhibit unique pharmacophoric features including conformational flexibility and spatial orientation within the binding sites of the targeted proteases. The present invention also discloses methods for treating SARS-CoV-2 infections, comprising administering to the subject in need thereof a therapeutically effective amount of the compound, or a pharmaceutically acceptable salt thereof, and one or more pharmaceutical excipients.


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