The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2023
Filed:
Jun. 12, 2018
Applicant:
Georgia Tech Research Corporation, Atlanta, GA (US);
Inventors:
Christoph J. Fahrni, Atlanta, GA (US);
Adam M. McCallum, Atlanta, GA (US);
Michael Thomas Morgan, Atlanta, GA (US);
Assignee:
Georgia Tech Research Corporation, Atlanta, GA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); G01N 21/77 (2006.01); G01N 33/58 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6428 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01); G01N 21/77 (2013.01); G01N 33/582 (2013.01); A61K 49/0021 (2013.01); G01N 2021/6439 (2013.01); G01N 2021/7786 (2013.01);
Abstract
The compounds relate to zinc-sensitive fluorescent probes, compositions and methods utilizing the same. Such compounds provide an emission-ratiometric fluorescence response upon binding of an analyte. In some embodiments, compounds can be used for two-photon excitation microscopy or conventional fluorescence microscopy. The compounds described herein can also contain one or more functional groups to improve the emission-ratiometric fluorescence response.