The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 14, 2023

Filed:

Jul. 20, 2022
Applicant:

Angle Europe Limited, Guildford, GB;

Inventors:

Alexandre Izmailov, Etobicoke, CA;

Brian Pak, Richmond Hill, CA;

Tomoyuki Sen, Toronto, CA;

Paul Timothy Smith, Acton, CA;

Assignee:

ANGLE EUROPE LIMITED, Guildford, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/30 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
G01N 1/30 (2013.01); B01L 3/502753 (2013.01); B01L 3/502761 (2013.01); B01L 2200/0647 (2013.01); B01L 2300/0822 (2013.01); B01L 2300/0832 (2013.01); B01L 2400/088 (2013.01);
Abstract

The present disclosure provides a cell harvesting method and device for the efficient sedimentation and retention of cells from liquid samples onto a solid support with low cell losses and low impact on cell morphology. The device has two configurations, one being for use in a centrifuge to centrifuge the sample, a second for controlled release of the liquid post centrifugation. The device includes a base to hold a solid support that receives cells on a top surface thereof that releasably holds a fluid chamber which has a first opening with a gasket surrounding the opening with that bears against a top surface of the support. An opening receives the liquid sample and the gasket defines an area into which the targeted cells deposit. A first cap closes the second opening during centrifugation. Post centrifugation the first cap is removed and a fluid absorbing element and cap, designed to provide controlled removal of the liquid and to prevent positioning of a tip of the absorbing element to a distance from the solid support shorter than a predefined distance is inserted into the fluid chamber.


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