The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2023
Filed:
Mar. 19, 2020
Applicant:
Grail, Llc, Menlo Park, CA (US);
Inventors:
Eugeni Namsaraev, Palo Alto, CA (US);
Maneesh Jain, San Francisco, CA (US);
Assignee:
GRAIL, LLC, Menlo Park, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6806 (2018.01); C12Q 1/6816 (2018.01); C12Q 1/6827 (2018.01); C12Q 1/6874 (2018.01); C12N 15/10 (2006.01); C12N 15/11 (2006.01); C12Q 1/6837 (2018.01); C12Q 1/6855 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6806 (2013.01); C12Q 1/6816 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6874 (2013.01); C12N 15/10 (2013.01); C12N 15/11 (2013.01); C12N 2310/531 (2013.01); C12Q 1/6837 (2013.01); C12Q 1/6855 (2013.01);
Abstract
Provided herein are methods for enriching a biological sample for a target nucleic acid, and analyzing the nucleic acid. In some cases, a biological sample is enriched for target nucleic acids associated with a cancer or tumor. In some cases, a biological sample is enriched for target nucleic acids, and the target nucleic acids vary in length. In some cases, one or more probes are used to enrich the biological sample for the target nucleic acid. In some cases, one or more probes hybridize to one or more ends of a target nucleic acid.