The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2023
Filed:
Apr. 15, 2021
Applicant:
Neubase Therapeutics, Inc., Pittsburgh, PA (US);
Inventors:
Danith H. Ly, Pittsburgh, PA (US);
Shivaji A. Thadke, Pittsburgh, PA (US);
Ramesh U. Batwal, Pittsburgh, PA (US);
Dietrich A. Stephan, Pittsburgh, PA (US);
Assignee:
NEUBASE THERAPEUTICS, INC., Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); C12N 15/113 (2010.01); A61K 51/04 (2006.01); A61P 25/28 (2006.01); A61K 9/00 (2006.01); G01N 33/68 (2006.01); G01N 30/72 (2006.01); C07K 5/097 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 9/0085 (2013.01); A61K 51/0491 (2013.01); A61P 25/28 (2018.01); C07K 5/0821 (2013.01); C07K 14/003 (2013.01); G01N 30/7233 (2013.01); G01N 33/6896 (2013.01); A61K 38/00 (2013.01); C12N 2310/3181 (2013.01);
Abstract
The present disclosure relates to compounds useful for the detection or modulation of target nucleic acids, including DNA and RNA. The present disclosure further relates to methods for treatment of trinucleotide repeat disorders, which can include administration of oligonucleotide analogues that can bind pathogenic nucleotide repeats in DNA or RNA.