The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 14, 2023

Filed:

Feb. 05, 2018
Applicants:

National Cancer Center Japan, Tokyo, JP;

Kyoto University, Kyoto, JP;

Takeda Pharmaceutical Company Limited, Osaka, JP;

Inventors:

Tetsuya Nakatsura, Chiba, JP;

Toshiaki Yoshikawa, Chiba, JP;

Yasushi Uemura, Chiba, JP;

Kyoko Fukuda, Chiba, JP;

Shin Kaneko, Kyoto, JP;

Atsutaka Minagawa, Kyoto, JP;

Yoshiaki Kassai, Kanagawa, JP;

Atsushi Matsuda, Cambridge, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61P 35/00 (2006.01); A61K 35/17 (2015.01); C07K 14/725 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0638 (2013.01); A61K 35/17 (2013.01); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C12N 15/86 (2013.01); C12N 2506/45 (2013.01);
Abstract

Provided is a T cell receptor capable of binding to a peptide having the amino acid sequence shown in SEQ ID NO: 27 or a complex of the peptide and HLA-A24. A T cell receptor capable of binding to a peptide having the amino acid sequence shown in SEQ ID NO: 28 or a complex of the peptide and HLA-A02. Disclosed T cell receptors are useful in treating or avoiding cancers which are associated with expression of glypican-3.


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