The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 14, 2023

Filed:

Jun. 04, 2018
Applicants:

Ablynx N.v., Ghent-Zwijnaarde, BE;

Merck Patent Gmbh, Darmstadt, DE;

Inventors:

Soren Steffensen, Etterbeek, BE;

Gerald Beste, Ghent, BE;

Guy Hermans, Merelbeke, BE;

Hans Gühring, Geisenheim, DE;

Christoph Ladel, Darmstadt, DE;

Lars Toleikis, Kleinniedesheim, DE;

Assignees:

Ablynx N.V., Zwijnaarde, BE;

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); C07K 16/18 (2006.01); A61P 19/02 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61P 19/02 (2018.01); C07K 16/40 (2013.01); C07K 2317/22 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/569 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C07K 2319/00 (2013.01);
Abstract

The present invention relates to immunoglobulins that specifically bind Aggrecan and more in particular to polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the immunoglobulins of the present invention inhibit the activity of Aggrecan.


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