The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 14, 2023

Filed:

Oct. 04, 2017
Applicant:

University of Florida Research Foundation, Incorporated, Gainesville, FL (US);

Inventors:

Gregory Hudalla, Gainesville, FL (US);

Sabrina Freeman, Gainesville, FL (US);

Antonietta Restuccia, Edmond, OK (US);

Margaret Mary Fettis, Gainesville, FL (US);

Evelyn R. Bracho-Sanchez, San Francisco, CA (US);

Shaheen Farhadi, Gainesville, FL (US);

Benjamin G. Keselowsky, Gainesville, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C12N 9/02 (2006.01); C07K 14/00 (2006.01); C12N 15/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4726 (2013.01); C07K 14/00 (2013.01); C12N 9/0069 (2013.01); C12N 15/00 (2013.01); C12Y 113/11052 (2013.01); C12Y 113/12007 (2013.01); A61K 38/00 (2013.01); C07K 2319/33 (2013.01); C07K 2319/73 (2013.01);
Abstract

Provided herein are targeted effector fusion proteins, complexes thereof, and uses thereof. The targeted effector fusion proteins can include an effector protein that can be linked to a targeting moiety. Monomer targeted effector fusion proteins can form homogeneous or heterogeneous complexes. The targeted effector fusion proteins and complexes thereof can be formulated as pharmaceutical formulations. The targeted effector fusion proteins, complexes thereof, and formulations thereof can be administered to a subject in need thereof.


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