The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2023
Filed:
Jun. 20, 2018
Genentech, Inc., South San Francisco, CA (US);
Zhonghua Pei, South San Francisco, CA (US);
Richard Pastor, South San Francisco, CA (US);
Lewis Gazzard, South San Francisco, CA (US);
Brendan Parr, South San Francisco, CA (US);
Wendy Liu, South San Francisco, CA (US);
Rohan Mendonca, South San Francisco, CA (US);
Guosheng Wu, Beijing, CN;
Po-wai Yuen, Beijing, CN;
GENENTECH, INC., South San Francisco, CA (US);
Abstract
Presently provided are inhibitors of cellularly expressed TD02 and IDO1, and pharmaceutical compositions thereof, useful for modulating an activity of tryptophan 2,3 dioxygenase and indoleamine 2,3-dioxygenase 1; treating immunosuppression; treating a medical conditions that benefit from the inhibition of tryptophan degradation; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; and treating tumor-specific immunosuppression associated with cancer.