The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 14, 2023

Filed:

Mar. 19, 2020
Applicant:

Vertex Pharmaceuticals Incorporated, Boston, MA (US);

Inventors:

Nadia M. Ahmad, Didcot, GB;

Corey Anderson, Brighton, MA (US);

Vijayalaksmi Arumugam, San Marcos, CA (US);

Iuliana Luci Asgian, San Diego, CA (US);

Joanne Louise Camp, Didcot, GB;

Lev Tyler Dewey Fanning, San Marcos, CA (US);

Sara Sabina Hadida Ruah, La Jolla, CA (US);

Dennis Hurley, San Marcos, CA (US);

Yvonne Schmidt, San Diego, CA (US);

David Shaw, Oxford, GB;

Urvi Patel, San Diego, CA (US);

Stephen Andrew Thomson, Del Mar, CA (US);

Lidio Marx Carvalho Meireles, San Marcos, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 235/64 (2006.01); C07C 237/42 (2006.01); C07D 307/86 (2006.01); C07D 239/42 (2006.01); C07D 213/69 (2006.01); C07D 213/82 (2006.01); C07D 213/89 (2006.01); C07D 239/34 (2006.01); C07D 307/79 (2006.01); C07D 317/46 (2006.01); C07D 405/12 (2006.01); A61K 31/165 (2006.01); C07D 213/81 (2006.01);
U.S. Cl.
CPC ...
C07C 235/64 (2013.01); A61K 31/165 (2013.01); C07C 237/42 (2013.01); C07D 213/69 (2013.01); C07D 213/81 (2013.01); C07D 213/82 (2013.01); C07D 213/89 (2013.01); C07D 239/34 (2013.01); C07D 239/42 (2013.01); C07D 307/79 (2013.01); C07D 307/86 (2013.01); C07D 317/46 (2013.01); C07D 405/12 (2013.01); C07B 2200/05 (2013.01); C07C 2601/02 (2017.05);
Abstract

Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.


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