The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2023
Filed:
Mar. 09, 2018
University of Louisville Research Foundation, Inc., Louisville, KY (US);
Georgia Tech Research Corporation, Atlanta, GA (US);
Haval Shirwan, Louisville, KY (US);
Andres J. Garcia, Atlanta, GA (US);
Esma S. Yolcu, Louisville, KY (US);
Hong Zhao, Louisville, KY (US);
Devon Headen, Atlanta, GA (US);
University of Louisville Research Foundation, Inc., Louisville, KY (US);
Georgia Tech Research Corporation, Atlanta, GA (US);
Abstract
Described herein are FasL-engineered biomaterials, as well as methods of making and using such FasL-engineered biomaterials, such as for immunomodulation, such as for inducing immunosuppression and specific immune tolerance, such as for preventing or reducing the risks of rejection of cellular or tissue grafts and/or the treatment of autoimmune disorders such as Type I diabetes. In specific embodiments, the FasL-engineered biomaterials are biotinylated microgels bound to SA-FasL.