The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2023
Filed:
Oct. 20, 2020
Applicant:
The University of Toledo, Toledo, OH (US);
Inventors:
William A. Maltese, Toledo, OH (US);
Zehui Li, Toledo, OH (US);
Christopher J. Trabbic, Toledo, OH (US);
Paul W. Erhardt, Toledo, OH (US);
Assignee:
The University of Toledo, Toledo, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); C12N 5/00 (2006.01); C12N 1/38 (2006.01); A61K 31/53 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 31/53 (2013.01); A61K 31/5377 (2013.01); C12N 1/38 (2013.01); C12N 5/0006 (2013.01); C12N 2500/30 (2013.01); C12N 2501/06 (2013.01);
Abstract
Vacuole- or exosome-inducing indole-based chalcone and substituted triazole-hydrazone compounds that induce endosomal vacuolization and increase exosome yield, but do not trigger growth arrest or cell death, and methods of making and using are described.