The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2023
Filed:
Mar. 23, 2018
Applicant:
Eisai R&d Management Co., Ltd., Tokyo, JP;
Inventors:
Yasuhiro Funahashi, Tsukuba, JP;
Tadashi Kadowaki, Tsukuba, JP;
Junji Matsui, Tsukuba, JP;
Jason S. Simon, Woodcliff Lake, NJ (US);
Lucy Xu, Woodcliff Lake, NJ (US);
Assignee:
Eisai R&D Management Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/574 (2006.01); C12Q 1/6886 (2018.01); A61K 31/47 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57407 (2013.01); A61K 31/47 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57438 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01);
Abstract
Biomarkers are provided that are predictive of a subject's responsiveness to a therapy comprising lenvatinib or a pharmaceutically acceptable salt thereof (e.g., lenvatinib mesylate). The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for a subject having cancer (e.g., thyroid cancer, kidney cancer), suspected of having cancer, or at risk of developing cancer.