The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2023
Filed:
May. 12, 2017
Applicant:
Leibniz-institut Für Polymer-forschung Dresden E.v., Dresden, DE;
Inventors:
Heather Weber, Dresden, DE;
Mikhail Tsurkan, Dresden, DE;
Valentina Magno, Dresden, DE;
Uwe Freudenberg, Dresden, DE;
Carsten Werner, Dresden, DE;
Assignee:
LEIBNIZ-INSTITUT FÜR POLYMER-FORSCHUNG DRESDEN E.V., Dresden, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/071 (2010.01); C12M 3/00 (2006.01); G01N 33/50 (2006.01); C12N 11/04 (2006.01); C12N 5/0775 (2010.01); C12M 1/32 (2006.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0062 (2013.01); C12M 21/08 (2013.01); C12M 23/12 (2013.01); C12N 5/0663 (2013.01); C12N 5/0668 (2013.01); C12N 5/0686 (2013.01); C12N 5/0687 (2013.01); C12N 5/0696 (2013.01); C12N 11/04 (2013.01); G01N 33/5088 (2013.01); C12N 2500/50 (2013.01); C12N 2501/734 (2013.01); C12N 2501/91 (2013.01); C12N 2502/25 (2013.01); C12N 2502/256 (2013.01); C12N 2502/28 (2013.01); C12N 2510/04 (2013.01); C12N 2513/00 (2013.01); C12N 2533/30 (2013.01);
Abstract
The invention relates to a method for the formation of renal tubules by embedding individual renal cells into a synthetic hydrogel, which is based on polyethylene glycol as a component, and the culturing of the cells until tubule structures are formed. The culturing can be continued until the obtained tubule structures correspond in terms of size, structure, morphology and functionality to adult human renal tubules or are at least similar thereto.