The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2023
Filed:
May. 04, 2018
Applicants:
City of Hope, Duarte, CA (US);
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Assignees:
CITY OF HOPE, Duarte, CA (US);
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); A61P 35/00 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
C07K 16/3061 (2013.01); A61K 39/39558 (2013.01); A61P 35/00 (2018.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/35 (2013.01); C07K 2317/522 (2013.01); C07K 2317/524 (2013.01); C07K 2317/526 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2319/30 (2013.01);
Abstract
Provided herein are, inter alia, compositions and methods for the treatment of cancer. The compositions include, for example, an antibody variable domain or antibody construct, inter alia, useful for targeting and killing cancer cells. Due to their ability to differentially bind cancer cells versus non-cancer cells, the compositions provided herein may be used, for example, for therapeutic and diagnostic purposes.