The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2023
Filed:
Nov. 21, 2017
Merck Patent Gmbh, Darmstadt, DE;
Christel Iffland, Arlington, MA (US);
Christina Esdar, Darmstadt, DE;
Xinyan Zhao, Bedford, MA (US);
Qi An, Nashua, NH (US);
Johannes Yeh, Billerica, MA (US);
Gang Hao, Belmont, MA (US);
Lars Toleikis, Kleinniedesheim, DE;
Vanita Sood, Somerville, MA (US);
David Nannemann, Woburn, MA (US);
Robin Lytle, Acton, MA (US);
Bjoern Hock, Maintal, DE;
Other;
Abstract
The present invention relates to antibodies with specificity for FGFR1. More particularly, the invention relates to monoclonal antibodies that bind specifically to and neutralize human, macaque and mouse forms of FGFR1 with high affinity. The invention also relates to nucleic acids encoding said antibodies, vectors for expression of these nucleic acids, and host cells for producing said antibodies. Further, the invention relates to the use of said antibodies in the diagnosis and/or treatment of cancers.