The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 07, 2023

Filed:

Jul. 02, 2018
Applicant:

Sirius Therapeutics, Inc., Boston, MA (US);

Inventors:

Sukumar Sakamuri, San Diego, CA (US);

Curt W. Bradshaw, San Diego, CA (US);

Dingguo Liu, San Diego, CA (US);

Laxman Eltepu, San Diego, CA (US);

Assignee:

SIRIUS THERAPEUTICS, INC., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/11 (2006.01); C07H 19/213 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
C07H 19/11 (2013.01); C07H 19/213 (2013.01); C07H 21/04 (2013.01);
Abstract

Disclosed are chiral phosphoramidite auxiliary compositions for diastereoselective synthesis of stereochemically enriched oligonucleotides, and nucleoside phosphoramidite compounds comprising the same. Exemplary structures of the chiral phosphoramidite auxiliary compositions include Formulas (IA) and (IB).


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