The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2023
Filed:
Aug. 24, 2018
Applicant:
The Royal Institution for the Advancement of Learning/mcgill University, Montreal, CA;
Inventors:
Michel L. Tremblay, Montreal, CA;
Kelly-Anne Pike, Dollard-des-Ormeaux, CA;
Luis Alberto Perez Quintero, L'île-Bizard, CA;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/6553 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C07F 9/655354 (2013.01); C12N 5/0636 (2013.01);
Abstract
The invention encompasses ex vivo method of stimulating isolated memory T-cell, tumor-infiltrating lymphocyte (TIL), T cell receptor (TCR) engineered cell, and/or chimeric antigen receptor (CAR) engineered cell with compounds of Formula I below, which are inhibitors of the TC-PTP enzyme.